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With a people-first culture, we encourage and support employee engagement and empowerment. We are committed to creating a dynamic and collaborative environment that supports and rewards creativity, innovation and enthusiasm. We recognize the wisdom that, when one of us thrives, we all thrive.

Interested in joining our amazing team, please submit your resume to . Are you in?

Current Job Openings

Full-Time - Research Associate – Fermentation

Location: San Diego, California 92121
Position: Full-Time, Regular Employee
Required Education: B.Sc. in Chemical Engineering, Bioengineering, Microbiology or Fermentation Science
Job Code: FE1801

Description:
Nucelis Inc. is looking for an experienced Fermentation Research Associate to join our fermentation process development team. This person will play a hands-on roll among operating our lab and pilot scale fermentations, collecting and processing samples, operating analytical equipment, preparing fermentation experiment documents, and participating in data analysis and process development/improvement discussions. The job will also include some general lab duties such as stocking/ ordering supplies, washing glassware and media preparation. Nucelis is focused on delivering naturally sourced and sustainable solutions to the personal care, nutrition and flavor and fragrance markets. Nucelis’ business model is to work with partners to apply our Rapid Trait Development System RTDS™ a suite of proprietary, non-GMO precision gene editing technologies, coupled with extensive fermentation and downstream process development expertise to improve the economics of manufacture of microbial fermentation products.

The successful candidate will be responsible for running lab scale (and pilot scale as needed) fermentations, including media preparation, vessel cleaning and assembly, sampling, process monitoring, and data recording/analysis. Respond to out-of-spec fermentation parameters in a timely manner, troubleshoot equipment or process issues and provide solutions.

  • Process and run fermentation analytical samples including OD600, Gallery (glycerol, ammonium, glucose) analysis, and HPLC analysis. Maintain and design fermentation run documentation including batch sheets, log sheets, and run data analysis sheets.
  • Contribute to fermentation process improvement activities using a data driven approach.
  • Collaborate cross-functionally with strain development and downstream process development teams to ensure strong linkages between fermentation and upstream and downstream technology functions.

Requirements:

  • Bachelor’s degree in Chemical Engineering, Bioengineering, Microbiology, Fermentation Science, or related field with at least 2 years of fermentation experience is required.
  • Experience setting up and operating lab scale bioreactors such as Bioflo 310s, DasGip, and Dasbox units is required. Fermentation Pilot Plant experience is desired
  • Ability to prepare and follow fermentation batch sheets detailing media recipes is required.
  • Ability to have a flexible schedule working an offset shift part of the week to expand coverage of the fermentation runs including occasional light weekend duties.
  • Good sterile technique is required.
  • Experience operating analytical equipment including HPLC, Gallery autoanalyzer or similar equipment is desired.

Nucelis provides an attractive compensation and benefits package that includes medical/dental/vision, 401(k) plan, vacation and sick leave. If you enjoy working as part of a team and want to participate in this exciting research, please e-mail resume to referencing job code: FE1801.

Only candidates with work authorization in the United States will be considered.

Senior Research Specialist NEW

Location: San Diego, CA
Position: Full-Time, Regular Employee
Reports To: Director, Strain Development
Job Code: NU1803

Description:
Nucelis Inc. is a metabolic engineering company in San Diego, CA, focused on the construction of commercially useful strains of microorganisms. We are seeking a Senior Research Specialist or Scientist in our R&D team to develop sustainable products in microbial platforms for the food, flavor and fragrance, and personal care markets. Nucelis is one of the companies of Cibus, a biotechnology company with advanced technologies to precisely target and direct natural gene-editing processes.

We are seeking a Senior Research Specialist or Scientist in our R&D team to develop microbial hosts (especially yeasts) for the production of metabolites.

Position Responsibilities:

  • Metabolic engineering of microbial strains using a combination of genetic, synthetic biology/molecular cloning, transgenic expression, chromosomal gene editing and adaptive evolution methods. Apply metabolic engineering and bioinformatics approaches to identify desired changes in pathways, regulatory networks, and gene targets to meet program objectives.
  • Evaluation of strain performance in small scale fermenters and collaborate with the Fermentation, Downstream Processing and Analytical teams to facilitate successful scale-up.
  • Apply –OMIC technologies and metabolic modelling of strain performance to guide iterative refinement of strains.
  • Process improvement to increase the speed and throughput of strain generation and selection.

Knowledge, Experience, and Skills:

  • Bachelors/Masters/Ph.D. degree in a Microbiology, Molecular Biology, Genetics, Biochemical Engineering or equivalent relevant experience at a similar level required. A minimum of 8 years experience for Bachelors, 5 to 8 years experience with Masters, or a Ph.D. with 0+ years.
  • Proven track record of using genetic, microbial physiology, chemical, genomic and engineering approaches to optimize microbial strains in which multiple genes have been precisely re-engineered. This includes identification of key mutations from evolved populations and balanced stacking of desirable traits using breeding and modern molecular approaches.
  • Experience application and development of gene editing technologies (e.g. CRISPR-Cas9).
  • Experience with Yarrowia lipolytica strongly preferred, and being nimble in adapting to new microbial systems and tools.
  • The successful candidate will have the personality compatible with a startup, including flexibility, good interpersonal and communication skills, and the ability to quickly adapt in a fluid environment while building an infrastructure.

Nucelis provides an attractive compensation and benefits package that includes medical/dental/vision, 401(k) plan, vacation and sick leave. If you enjoy working as part of a team and want to participate in this exciting research, please e-mail resume to and put down job code: NU1803.

Only candidates with work authorization in the United States will be considered.

Nucelis is an equal opportunity employer.

Benefits

We provide an attractive compensation and benefits package that includes:

  • Medical, Dental, and Vision Plans
  • Health Spending Account (HSA)
  • 401(k) Plan
  • Voluntary Additional Insurance Benefits
  • Vacation and Sick Leave
  • Holidays
  • Recognition Programs
  • On-Site Fitness Center

Recruiter Policy

It is imperative that you read the following policy before contacting us:

Cibus’ Human Resources Department is the focal point for all recruiting and hiring at the Company. If your recruitment agency is interested in establishing a relationship with Nucelis, we require that you work directly with the Cibus Human Resources Department.

Presenting candidates to Nucelis employees other than those who are part of our Human Resources Department is not appropriate.

Nucelis does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from a recruitment firm if a signed agreement is in place with that firm at the inception of the recruiting effort for each specified position. An unsolicited resume sent to Nucelis from a recruiter does not constitute any type of relationship between the recruiter/recruitment firm and Nucelis, and does not obligate Nucelis to pay fees if we hire the candidate.

For consideration, please send your company information, a copy of your standard search agreement, and references to or mail to:

CIBUS
Human Resources Department
6455 Nancy Ridge Drive
San Diego, CA 92121.